They are also indicated in chronic anterior uveitis and corneal injury from chemical, radiation or thermal burns, or penetration of foreign bodies. Ocular steroids are indicated in inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe where the inherent risk of steroid use in certain infective conjunctivitis is accepted to obtain a diminution in edema and inflammation. INDICATIONS AND USAGE:įor steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial ocular infection exists. The relative potency of corticosteroids depends on the molecular structure, concentration, and release from the vehicle. When a decision to administer both a corticoid and an antimicrobial is made, the administration of such drugs in combination has the advantage of greater patient compliance and convenience, with the added assurance that the appropriate dosage of both drugs is administered, plus assured compatibility of ingredients when both types of drugs are in the same formulation and, particularly, that the correct volume of drug is delivered and retained. Since corticoids may inhibit the body’s defense mechanism against infection, a concomitant antimicrobial drug may be used when this inhibition is considered to be clinically significant in a particular case. PRESERVATIVE ADDED: Benzalkonium Chloride 0.004% CLINICAL PHARMACOLOGY:Ĭorticoids suppress the inflammatory response to a variety of agents and they probably delay or slow the healing. Hydrochloric Acid and/or Sodium Hydroxide may be added to adjust pH (3.5 – 6.0). Each mL Contains: ACTIVES: Neomycin Sulfate (equivalent to 3.5 mg Neomycin), Polymyxin B Sulfate equal to 10,000 polymyxin B units, Dexamethasone 1 mg (0.1%) INACTIVES: Sodium Chloride, Hypromellose, Polysorbate 20, Purified Water.
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